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Klamentin 250

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Quick Information

  • Brand Name :Klamentin
  • Model Number :4KMB01
  • Place of Origin :Vietnam

Description

DESCRIPTION
Antibiotic

COMPOSITION
Amoxicillin .................................. 250 mg
Clavulanic Acid .............................31.25 mg
Excipients ..q.s............................... 1 sachet
(Aspartame, isomalt, sodium CMC, orange flavour, sodium benzoate, anhydrous lactose)
DOSAGE FORM
Powder
PRESENTATION
Box of 12 sachets x 1.5 g of powder
ACTIONS
Amoxicillin is a semi-synthetic antibiotic with a broad-spectrum of antibacterial activity against many Gram-positive and Gram-negative microorganisms. However, amoxicillin is susceptible to degradation from -lactamases; therefore, amoxicillin has no action o­n-lactamase-producing bacteria.
Clavulanic Acid possesses the ability to inactivate a wide range of -lactamases commonly found in bacteria resistant to penicillins and cephalosporins.
The combination of Clavulanic Acid and Amoxicillin in KLAMENTIN protects amoxicillin from degradation by -lactamase enzymes, and extends the antibacterial spectrum of amoxicillin including bacteria resistant to amoxicillin, penicillin and cephalosporin.
KLAMENTIN has a bactericidal action o­n a wide range of bacteria consisting of:
Gram-positive aerobic bacteria: Bacillus anthracis, Corynebacterium species, Enterococcus faecalis, Enterococcus faecium, Listeria monocytogenes, Nocardia asteroides, Staphylococcus aureus, Coagulase negative staphylococci (consisting of Staphylococcus epidermidis), Streptococcus agalactiae, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus species, Streptococcus viridans.
Gram-positive anaerobic bacteria: Clostridium species, Peptococcus species, Peptostreptococcus species.
Gram-negative aerobic bacteria: Bordetella pertussis, Brucella species, Escherichia coli, Gardnerella vaginalis, Haemophilus influenzae, Helicobacter pylori, Klebsiella species, Legionella species, Moraxella catarrhalis (Branhamella catarrhalis), Neisseria gonorrohoeae, Neisseria meninggitidis, Pasteurella multocida, Proteur mirabilis, Proteur vulgaris, Salmonella species, Shigella species, Vibrio cholerae, Yersinia enterocollitica.
Gram-negative anaerobic bacteria: Bacteroides species (consisting of Bacteroides fragilis), Fusobacterum species.
Other bacteria: Borrelia burgdorferi, Chlamydiate, Leptospira interohaemorrhagia, Treponema pallidum
INDICATIONS
For short-term treatment of upper respiratory tract infections (consisting of ENT infections) such as tonsillitis, sinusitis, otitis media;lower respiratory tract infections such as acute and chronic bronchitis, chronic bronchopneumonia, chronic lobar pneumonia. Urogenital infections such as cystitis, urethritis, pyelonephritis, female genital tract infections. Skin and soft tissue infections such as furuncles and abscesses, cellulitis, infected wounds. Bone and joint infection such as endostitis.KLAMENTIN has a bactericidal action o­n many strains of bacteria including -lactamase-producing strains resistant to ampicillin and amoxicillin.
CONTRAINDICATIONS
- Hypersensitivity to penicillins and cephalosporins.
- Severe hepatic and renal impairment.
- Patients with history of jaundice or hepatic dysfunction when taking penicillins.
- Infectious mononucleosis.
PRECAUTIONS
- Before treatment with KLAMENTIN, patients should be carefully asked about their known hypersensitivity to penicillins, cephalosporins or other allergenic substances.
- Serious hypersensitive reactions and sometimes risky to survival (anaphylactic reactions) in patients treated with penicillins, this reaction rarely occurs in patients taken drug orally.
- Breast-feeding and pregnant women.
- The doses should be adjusted in patients with renal impairment.
- Prolonged treatment may cause surinfection.
INTERACTIONS
- Probenecid decreases renal tubular secretion of amoxicillin; thus, may result in increased blood levels of amoxicillin.
- Allopurinol increases allergic incidence of amoxicillin.
- Caution should be taken in patients being treated with anticoagulants.
- KLAMENTIN may decrease the effect of contraceptives by oral route.
- KLAMENTIN may result in false-positive test for glucose in the urine with Clinitest, Benedict's solution, Fehling's solution
ADVERSE EFFECTS
Gastrointestinal disturbances (diarrhoea, dyspepsia, nausea, vomiting), pseudomembranous colitis, candidosis, thrombocytopenia, hypoleukemia, eosinophilia, granulocytopenia, hemolytic anemia.
Rarely (the drug administration must be discontinued): allergic reactions (prurigo, urticaria, erythema), Stevens-Johnson syndrome, Lyell syndrome, angioedema, dermatitis, hepatitis and obstructive jaundice, acute renal impairment, interstitial nephritis.
Inform your physician about any adverse effects occur during the treatment.
DOSAGE & ADMINISTRATION
The doses are referred to amoxicillin.
Children under 30 months of age: 80 mg / kg body-weight / day, in 3 divided doses.
Not exceed 3 g / day.
Or as directed by the physician.
Read the directions carefully before use.
Consult the physician for more information.
This drug is o­nly used with the physician's prescription.
SHELF-LIFE
24 months from the manufacturing date.
STORAGE CONDITIONS
Store in cool dry place; protected from light
SPECIFICATIONS
Complies with the manufacturer's.

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  • Klamentin 250

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Klamentin 250

Klamentin 250

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