Metenolone enanthate (or methenolone enanthate) is a dihydrotestosterone (DHT) based anabolic steriod. It is an ester derivative of methenolone sold commonly under the brand names Primobolan (tablet form) or Primobolan Depot (injectable). When it interacts with the aromatase enzyme it does not form any estrogens. It is used by people who are very susceptible to estrogenic side effects, having lower estrogenic properties than nandrolone. Methenolone, in form of enanthate and acetate, is available as an injection or as an oral respectively. The injection is naturally regarded as having a higher bioavailability. It is an enanthate ester which is quite long-acting. Because it by-passes hepatic breakdown on the first pass, it also has a higher survival rate. The tablets are in a short-lived acetate form. Methenolone is not 17-alpha-alkylated, but 1-methylated for oral bioavailability. This reduces the stress on the liver, but also the availability. It is considered one of the safer steriods, meaning it has few side effects. Methenolone has no estrogenic side effects, and its effects on cholesterol levels are minimal. In doses of 200 mg per week or less (intramuscular) blood pressure is rarely altered. It is possibly one of the safer anabolic steriods for females due to very low virilization effects in short-term usage. Methenolone is also not overly suppressive of the hypothalamic-pituitary-gonadal axis, although how suppressive is debatable. For this reason, many bodybuilders use it in between steriod cycles during their "off-time" to help maintain their gains and strength. The long term safety of such a practice is possibly dangerous and can lead to permanent suppression of the HPTA.
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