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Top Quality 99% Antifungal Griseofulvin Cas 126-07-8

Price
US $ 1
Min Order Quantity 10g / kg
Port shanghai
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Quick Information

  • Brand Name :made-in-china
  • Place of Origin :China
  • CAS No. :126-07-8
  • Purity :99%
  • sample :free
  • market :worldwide

Description

Top Quality 99% Antifungal Pharmaceutical Raw Materials GRISEOFULVIN CAS 126-07-8 


Quick Details for GRISEOFULVIN


GRISEOFULVIN Product Name: GRISEOFULVIN
GRISEOFULVIN Synonyms: (+)-GRISEOFULVIN;GRISEOFULVIN;[2S-TRANS]-7-CHLORO-2,4,6-TRIMETHOXY-6'-METHYLSPIRO[BENZOFURAN-2(3H), 1'(2)-CYCLOHEXANE]-3,4'-DIONE;(2S)-TRANS-7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYLSPIRO(BENZOFURAN-2[3H],1'-[2]CYCLOHEXENE)-3,4'-DIONE;7-CHLORO-2',4,6-TRIMETHOXY-6'-METHYL-, (1'S-TRANS)-SPIRO(BENZOFURAN-2(3H),1'-(2)CYCLOHEXENE)-3,4'-DIONE;(+)-griseofulvi;(2s-trans)-7-chloro-2’,4,6-trimethoxy-6’-methylspiro[benzofuran-2(3h),1’-[2]cy;(2s-trans)-xy-6’-methyl 
GRISEOFULVIN CAS: 126-07-8 
GRISEOFULVIN MF: C17H17ClO6 
GRISEOFULVIN MW: 352.77 
GRISEOFULVIN EINECS: 204-767-4 
GRISEOFULVIN Product Categories: Intermediates & Fine GRISEOFULVIN Chemicals;Pharmaceuticals;Antifungal;Aromatics;Chiral Reagents;VERELAN;Inhibitors
GRISEOFULVIN Melting point : 218-220 °C(lit.)
Alpha : 354 º (c=1, dimethylform) 
GRISEOFULVIN Storage temp. : −20°C
GRISEOFULVIN Water Solubility  : practically insoluble
GRISEOFULVIN Chemical Properties : Crystalline Solid
GRISEOFULVIN Usage : adrenegic blocker, Ca channel blocker, coronary vasodilator, antiarrhythmic .
GRISEOFULVIN Usage : antifungal, inhibits mitosis in metaphase .
GRISEOFULVIN Usage : Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect of the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy. 
Usage : It is an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum .

GRISEOFULVIN Description

Griseofulvin is a non-polyene class antifungal antibiotics; it can strongly inhibit the mitosis of fungal cell and interfere with the fungal DNA synthesis; it can also bind to tubulin to prevent fungal cell division. It has been applied to clinical medicine since 1958 and has currently been widely used for treating the fungal infections of the skin and the stratum corneum with strong inhibitory effects on Trichophyton rubrum and Trichophyton tonsorans, etc. Griseofulvin is not only a widely used antibiotic for clinical treatment of fungal infections of the skin and cuticle, but also applied in agriculture for prevention and treatment of fungal diseases; for example, it has a special efficacy on treating a kind of candidiasis in apple which can cause infection during pollination.

GRISEOFULVIN Pharmacological Effects

In medicine, this product mainly has good antibacterial effect against Trichophyton, Microspores, and Epidermophyton fungi. However, it has no anti-bacterial effect on Candida, Cryptococcus, Histoplasma, Sporothrix, Blastomyces, and Coccidioides and so on. Mechanism of action of is drug is through interfering with the biosynthesis of nucleic acids of fungal and further inhibiting of its growth.

In agriculture, this product has good inhibitory effect on the Ascomycetes, Basidiomycetes, Deuteromycetes and some kinds of algae. However, it is not effective in treating oomycetes whose cell wall containing no chitin content. After spraying melons and other crops, it can be transferred into the branch, leaves and fruits through inner absorption, the absorption of water via rrot, as well as transpiration effect, and further preventing the fungal diseases; according to the study of Brandeis et al. (1946), at a concentration as low as even 10 mg/L or 1 mg/L, griseofulvin can already can make the mycelium of Bctrytis allill be stout, deformed and exhibit spiral bending, also cause: large number of abnormal branching; the development retardation of germinated spores, and loss of apical dominance; thus it has uptake therapeutic effects on a variety of plant diseases, especially powdery mildew, gray mold diseases; Griseofulvin has a more prominent antibacterial activity than the bactericidal activity.  
 

Our promise:

1.High quality and standard:

  • Standard: Enterprise Standard;
  • All Purity≥98%;
  • We are manufacturer and can provide high quality products with factory price.


2. Fast and safe delivery:

  • Parcel can be sent out within 24 hours after payment. Tracking number is available;
  • Secure and discreet shipment (EMS , DHL , TNT , FedEx , UPS). Various transportation methods for your choice;
  • Customs pass rate ≥99%;
  • We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.


3.Service:

  • Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their desire.
  • Market feedback and goods feedback will be appreciated, meeting customers's requirement is our responsibility.
  • High quality, competitive price, fast delivery, first-class service gain the trust and praise from the customers.
  • Flexible payment terms (Western Union , Money Gram , T/T , Bitcoin) makes you convenient at payment choice.

 

Additional Information
Contact Person : Ms. mandy
Skype njsteriod001
Whatsapp +86-17327098554
Discount Multiple items ordered one time
Larger quantity of each item

Price

  • Price Condition : FOB
  • Price : USD 1 / kg
  • Delivery Port : shanghai

Packaging & Delivery

  • Minimum Order : 10g

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  • Top Quality 99% Antifungal Griseofulvin Cas 126-07-8

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Top Quality 99% Antifungal Griseofulvin Cas 126-07-8

Top Quality 99% Antifungal Griseofulvin Cas 126-07-8

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