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Sell 3-Bromocinnamic acid

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  • Company Name :Wuhan LANDMARK Industrial Co., Ltd.
  • Membership :Free member
  • Registrarion Date :2019. 03. 14
  • CountryRegion:China
  • Address:jianan street, 18 Chengde Hebei, China
  • Phone / Fax:86-27-83916065  /  
  • Contact:Eason xiao
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Description

Synonyms:RARECHEM BK HC T307; TRANS-3-BROMOCINNAMIC ACID; M-BROMOCINNAMIC ACID; M-BROMOPHENYLACRYLIC ACID;BROMOCINNAMIC ACID,3-;3-BROMOCINNAMIC ACID; AKOS BBS-00006566; AKOS B004044
CAS NO.:32862-97-8
Formula:C9H7BrO2

Molecular weight: 227.05
EINECS NO.:251-267-7
Melting point: 177-179 °C
Appearance: Colorless crystal
Vapor pressure: 0.0±0.8 mmHg at 25°C
Refractive index: 1.648
Storage: Shading, confined preservation, dry, ensure good ventilation or exhaust in the workshop
Stability: Stable under normal temperature and pressure
Key words: 3-Bromocinnamic acid, spices, essence, Synthetic essence,

General description
3-Bromocinnamic acid is the metabolite of cinromide (3-bromo-N-ethylcinnamamide) and can be analysed in plasma by high-performance liquid chromatographic method.
Simultaneous determination of the anticonvulsants, cinromide (3-bromo-n-ethylcinnamamide), 3-bromocinnamamide, and carbamazepine in plasma by high-performance liquid chromatography.


Abstract
A high-performance liquid chromatographic method is described for monitoring plasma concentrations of cinromide (3-bromo-N-ethylcinnamamide) and its de-ethylated metabolite. Carbamazepine levels can be easily measured by the same technique. The N-isopropyl analogue of cinromide is used as internal standard, and all compounds are easily separated on a reversed-phase column operated at 55 degrees with a small-diameter pre-column maintained at the same temperature. The extraction is rapid and generally applicable to plasma and urine samples that are to be analyzed by reversed-phase chromatography. Short- and long-term reproducibility studies show less than 4% relative standard deviation for replicate determinations for all drugs. Limits of quantitation are 10-20 ng/ml with an internal standard concentration of 3 micrograms/ml. Another metabolite of cinromide, 3-bromocinnamic acid, which may have some anticonvulsant effect, can be analyzed simultaneously by buffering the mobile phase and adding an ion-pairing

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