Beta-cyclodextrin also named B-cyclodextrin,B-CD etc.it is the product of glucosyltransferase and starch , white crystalline powder , is the dextrin with 7 dextroses coonnected by alfa 1.4 bond. There are a hole in this molecule, which can react with lots of chemicals and form compound. The solubility of beta-cyclodextrin is 1.85. MP is 200,
Molecular formula :C6H10O57 ,( 1134.99 )
Pharmacenthcal Applications
1. Enhance drugs stability. Drugs easily metamorphose and lower or lose its effectiveness which are inflenced by temperature, humidity, light, microorganisms and othe external factors. When people tade drug, the drug will be strong acid hydrolysis in the stomach, or lost reactive role by enzymes and microorganisms in the alimentary canal, using Beta-cyclodextrin can change these shortcomings.
2. Prevent the oxidation and decomposition of drugs. Beta-cyclodextrin can be used to prevent drugs volatilixing, it is good for long-term storage of drugs, its suitable for oral tablets.
3. Improve drug solubity and biological utilization degrees Beta-cyclodextrin can improve drug solubility and increase medicament quantity in blood after taking the drug, Beta-cyclodextrin can also incrase the utilization of biological degrees, reducing the dosage of drugs.
4. Reduce the toxicity and side effects of drugs Beta-cyclodextrin can avoid drugs directly comtact with mucous membrane of stomach, which cant cause trouble with stomach. Beta-cyclodextrin also prevent drug dust hurting the skin.
5. Cover up the smell of drugs For example, ginseng have special smell with bitterness, it can disapper after using Beta-cyclodextrin .
6. Other using Beta-cyclodextrin can facilitate drugs preservation and transp
Spec | CP2020,USP,BP,PhEur |
---|---|
Quantity | 60000KGS |
Price | FOB Qindao,China USD2.53/KG |
Package | 20KGS/CARTON,25KG/ BAG, 1000KG/BAG |
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