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Anti Fungal Infection Drug Griseofulvin Pharmceutical USP Raw Powder

Min Order Quantity 10 grams /
Supply Ability 5000KG/Month
Port Guangzhou
Delivery Lead Time Within 12 Hours After Receiving Your Payment
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Quick Information

  • Brand Name :kafenbio
  • Model Number :albert@kafenbio.com
  • Place of Origin :China
  • CAS No. :126-07-8
  • Purity :99.5%
  • Email :albert@kafenbio.com
  • What's App :+8618011892373
  • Skype :kafenbiotech

Description

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1.Quick Details:

Product Name:(+)-Griseofulvin
CAS:126-07-8
MF:C17H17ClO6
MW:352.77
EINECS:204-767-4
Product Categories:Intermediates & Fine Chemicals;Pharmaceuticals;Antifungal;Aromatics;Chiral Reagents;VERELAN
Chemical Properties:Crystalline Solid

2.Product Description:

Griseofulvin (trade names: Gris-peg and Grifulvin V) is an orally administered antifungal drug. It is used both in animals and humans, to treat fungal infections of the skin (commonly known as ringworm) and nail fungus. It was discovered in the culture broth of certain species of the mold Penicillium in 1939.It is produced industrially by fermenting the fungus Penicillium patulum.It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system.

Griseofulvin, an antifungal agent, has been reported to inhibit proliferation of various types of cells. This compound has also been shown to strongly suppress the dynamic instability of individual microtubules via reduction of the rate and extent of the growing and shortening phases. The effects that Griseofulvin has on microtubules can cause mitotic arrest and abnormalities, such as multipolar spindles, misaligned chromosomes, and fragmented nuclei

3.Product Application:

1) adrenegic blocker, Ca channel blocker, coronary vasodilator, antiarrhythmic
2) antifungal, inhibits mitosis in metaphase
3) Griseofulvin is a spirobenzofuran produced by a number of Penicillium species, first isolated in the 1930s by Raistrick's group. Griseofulvin is a selective antifungal agent used to treat skin infections in animals and humans. Griseofulvin acts by binding to fungal tubulin and inhibiting the mitotic spindle. Griseofulvin's ability to bind to keratin is considered an important aspect of the metabolite's access to dermatophytic fungi. More recently, griseofulvin has become an important phenotypic marker in Penicillium taxonomy.
4) It is an antifungal drug. It is used both in animal and in humans, to treat rigworm infections of the skin and nails. It is derived from the mold Penicillium griseofulvum

4.Function:

1) Griseofulvin is an antifungal drug that is administered orally. It is used both in animals and in humans, to treat fungal infections of the skin (commonly known as ringworm) and nails. 
2) Potential for cancer treatment   
3) Griseofulvin is used orally only for dermatophytosis

5.COA:
 

Item Specification Test Results
Characteristics A white or yellowish-white, microfine powder Yellowish-white microfine powder
 
Melting  point About 220ºC 220.5ºC
Specific optical rotation +354°~+364° +361.1°
Identification Meets the requirements Meets the requirements
Check-up Particles size Meets the requirements Meets the requirements
Acidity 0.25g consumed 0.02mol/L NaOH not more than 1.0ml 0.6ml
Clarity and colour of solution The solution is clear and not more intensely coloured than reference solution Y4 clear Y5-Y6
Matter soluble in petroleum spirit ≤0.2% 0.10%
Sulphated ash ≤0.2% 0.08%
Related substances -CL:<0.60  -H:<0.15 -CL:0.23 -H:0.06
Loss on drying ≤1.0% 0.08%
Abnormal toxicity Meets the requirements Meets the requirements
Assay(on the anhydrous substance) 97.0%~102.0% 99.65%
Conclusion Qualified/ Complied with USP34

Price

  • Price Condition : CIF
  • Delivery Port : Guangzhou

Packaging & Delivery

  • Packing : Discreet and disguised
  • Delivery Lead Time : Within 12 Hours After Receiving Your Payment
  • Minimum Order : 10 grams
  • Supply Ability : 5000KG/Month

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  • Anti Fungal Infection Drug Griseofulvin Pharmceutical USP Raw Powder

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