EDC (N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide HCl)(CAS#25952-53-8),Introduction
1-Ethyl - (3-dimethylaminopropyl) carbodiimide hydrochloride, also known as EDC hydrochloride. The following is an introduction to its nature, purpose, manufacturing method, and safety information:
nature:
1. EDC hydrochloride is a white crystalline powder with weak acidity.
2. It is easily soluble in water and has good solubility in organic solvents such as alcohols and ethers.
3. EDC hydrochloride is stable at room temperature.
Purpose:
1. EDC hydrochloride is a commonly used Solvent reactant with a wide range of applications in organic synthesis.
2. As an activator, EDC hydrochloride can react with amino acids or phthalein bonds to generate acylation midbody, playing an important role in phthalein synthesis and protein modification.
3. As a coupling agent, EDC hydrochloride can couple acids and alcohols to form ester bonds, which are used to synthesize compounds such as esters, ethers, and imides.
4. Used for the synthesis of dyes and pigments.
Manufacturing method:
EDC hydrochloride can be obtained by reacting EDC with hydrochloric acid. During the specific operation, mix EDC with a sufficient amount of hydrochloric acid solution, stir and heat the reaction, and finally evaporate the solvent to obtain crystals of EDC hydrochloride.
Security information:
1. EDC hydrochloride may have irritating effects on the skin, eyes, and respiratory tract, so protective gloves, goggles, and masks should be worn.
2. Avoid direct inhalation or contact with EDC hydrochloride powder.
3. When using EDC hydrochloride, attention should be paid to good indoor ventilation to avoid inhaling its volatile gases.
4. When handling EDC hydrochloride, care should be taken to prevent it from being swallowed or ingested by mistake.
5. It should be stored in a dry and away from heat sources, avoiding contact with oxidants and flammable materials.
