The FX-5000™ Tension System is a patented, computerized, pressure-operated instrument that applies a defined controlled, static or variable duration cyclic tension, to cells growing in vitro. This system utilizes regulated vacuum pressure to deform flexible-bottomed culture plates.
When used with BioFlex® culture plates and cylindrical-shaped loading posts, this system applies an equibiaxial strain to the cells cultured in monolayer on the flexible-bottomed membrane of the BioFlex® culture well. Similarly, when used with UniFlex® culture plates and an Arctangle® loading post, this system applies a uniaxial strain. This system can also apply a gradient biaxial strain of up to 33% when used in the absence of loading posts.
Highlights
Apply equibiaxial or uniaxial tension to cells in 2D and 3D culture.
Simulate in vivo tissue strains and frequencies in an in vitro setting.
Contains state-of-the-art digital valves to automatically regulate and maintain pressure for a specified strain regimen.
Works with BioFlex®, Tissue Train®, UniFlex®, and 24-well HT BioFlex® series culture plates.
Multiple frequency, amplitude and waveform changes can be programmed in one regimen.
Drives up to four independent FlexLink® remote compression and/or tension controllers.
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Culture Plate
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Max Achievable Strain
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BioFlex
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21.8%
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Tissue Train
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20.8%
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UniFlex
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12.2%
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HT BioFlex
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15.0%
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No Loading Stations
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33%
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FX-5000™ Tension System includes:
- Host computer with monitor
- FlexSoft FX-5000™ software
- FX5K™ Tension FlexLink®
- Tension accessory package:
à BioFlex® baseplate and four gaskets
à BioFlex® Loading Stations™ with 25 mm diameter Loading Posts
à Four BioFlex® culture plates
à Drying filter, water trap, vacuum tubing, and grease/lubricant
Applications:
load analysis of biochemical reactions in a variety of cell stress stimuli,
For example: bone cells, lung cells, myocardial cells, blood cells, skin cells, tendon cells, ligament cells, cartilage cells, and bone cells,
Kidney bladder cells, smooth muscle cells / urothelial and urothelial cells, eye epithelial cells, trabecular meshwork cells, renal tubular epithelial cells,
Intestinal epithelial cells, epithelial cells and other cells in the stomach stretch tensile force loading.
BIO EXCELLENCE® INTERNATIONAL Tech Co.,Ltd
phone: 86-13261877206
Fax: 86-010-67529703
Mail:SLBY800◎163.COM
www.bio-goods.com
1.Flexcell FX5000 Compression system
Apply compression to tissue samples or 3D cell-seeded constructs and viewing real-time responses to mechanical load by StageFlexer microscopy devices .
2.Flexcell-FX5000-Tension system
A computer-regulated bioreactor that uses vacuum pressure to apply cyclic or static strain to cells cultured on flexible-bottomed culture plates and viewing real-time responses to mechanical load by StageFlexer microscopy devices .
3.Flexcell FX5000 TissueTrain system
3D cell culture in a gel matrix with or without cyclic uniaxial tension and viewing real-time responses to mechanical load by StageFlexer microscopy devices .
4.Flex Jr Tension system
A new computer-regulated bioreactor that uses vacuum pressure to apply cyclic or static strain to cells in microscope devices.
5.Flexcell® Fluid Shear Systems
Apply fluid shear stress to cells with laminar, pulsatile, or oscillating flow
6.Culture Plates & Slides
Flexible growth surfaces treated to promote cell attachment and growth of a variety of cell types. Covalently bonded surfaces: Amino, Collagen, Elastin, ProNectin, and Laminin.
